ImmunecellactivationinsevereCOVID-19resembleslupus
byEmoryUniversity,MedicalXpress,OCTOBER9,
埃默里大学,医学快报,年10月9日
SARS-CoV-2(shownhereinanelectronmicroscopyimage).Credit:NationalInstituteofAllergyandInfectiousDiseases,NIH
图为SARS-CoV-2(显示在电子显微镜图像中)。图片来源:国立过敏和传染病研究所
InseverecasesofCOVID-19,Emoryresearchershavebeenobservinganexuberantactivationofimmunecells,resemblingacuteflaresofsystemiclupuserythematosus(SLE),anautoimmunedisease.
埃默里研究人员观察到,在新冠肺炎的严重病例中,免疫细胞的旺盛激活类似于系统性红斑狼疮(一种自身免疫性疾病)的急性发作。
TheirfindingspointtowardsteststhatcouldseparatesomeCOVID-19patientswhoneedimmune-calmingtherapiesfromotherswhomaynot.TheyalsomaybegintoexplainwhysomepeopleinfectedwithSARS-CoV-2produceabundantantibodiesagainstthevirus,yetexperiencepoorout